New Paradigms in Diabetes Management From the Epicenter

New Paradigms: Business and Management

i Recent developments in information and communication technologies have brought in a new wave of changes in the business organizations. This change is primarily a social phenomenon, rather than a management or technology driven plan, which is percolating in a bottom-up manner-from individuals to businesses-and is directed towards building of collaborative culture and communities that transcend...

New paradigms in gastrointestinal stromal tumour management.

BACKGROUND Targeted agents have improved the prognosis for patients with advanced gastrointestinal stromal tumours (GISTs). Many patients exhibit intolerance or resistance to first-line therapy with imatinib mesylate. Sunitinib malate is approved multinationally for the treatment of advanced imatinib-refractory GIST. DESIGN This article reviews responses to imatinib and sunitinib reported in ...

Spectacular failure--a view from the epicenter.

New paradigms in patient blood management in surgery.

New treatments and shifting paradigms in differentiated thyroid cancer management.

BACKGROUND Although most thyroid cancer patients have an excellent prognosis, 10% of low-risk cancers and 25% of high-risk cancers recur, with mortality rates in excess of 50% at 3 years for aggressive thyroid cancer. Traditional paradigms including surgery, I¹³¹ ablation, and TSH suppression do not offer additional therapeutic options for cancers that fail these interventions. Risk stratificat...